Stevioside appear to be stable sweeteners. Stevioside, the main sweet component in the leaves of S. rebaudiana tastes about 300 times than sucrose (0.4% solution).
This plants leaves have been used for centuries to sweeten beverages and make tea. It has been shown that stevioside is not taken by the human body and none of the digestive enzyme from the gastro-intestinal tract different animals and man are able to degrade stevioside into steviol I, the aglycone of stevioside.
The significance of steviol is that, when metabolically activated, it produces a mutagen.
Steviol generation has been demonstrated in vitro with rat caecal flora and in vitro in rats but not in mammalian system systems. After several hours steviol was found in the blood of the animals, the maximum concentration occurring after 8 hours.
Stevioside is not approved by FDA as an additive nor accepted it as a GRAS substance, it cannot be used in the United States.
Stevioside as sweetener
What makes soft drinks so noteworthy is that, despite not being essential, their consumption continues to rise. They are entirely human inventions—both as a product and as a market. In fact, soft drinks were among the first branded goods to achieve truly global reach.
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